Kev loj hlob yam tseem ceeb yog cov khoom siv dag (man-made) chemicals uas txhawb kom cov hlwb sib faib thiab loj hlob. Muaj ntau ntau yam kev loj hlob sib txawv uas cuam tshuam rau ntau hom cell. Koj lub cev ua rau muaj kev loj hlob ib txwm muaj.
Kev loj hlob yam yog dab tsi?
Granulocyte-colony stimulating factor (G-CSF) yog tsim nyob rau hauv lub cev los ntawm lub cev tiv thaiv kab mob thiab txhawb kev tsim ntawm ib hom ntawm cov qe ntshav dawb, cov neutrophil. Neutrophils koom nrog hauv cov tshuaj tiv thaiv kab mob thiab ua lub luag haujlwm rau kev kuaj xyuas thiab rhuav tshem cov kab mob phem, kab mob, thiab qee cov fungi.
Qee qhov kev loj hlob kuj tseem tuaj yeem tsim hauv chav kuaj. Cov no tuaj yeem siv los txhawb kev tsim cov hlwb tshiab hauv cov neeg mob uas xav tau lawv.
Ntau hom G-CSF tuaj yeem siv tau:
- Lenograstim (Granocyte®)
- Filgrastim (Neupogen®)
- Lipegfilgrastim (Lonquex®)
- Pegylated filgrastim (Neulasta®)
Leej twg xav tau kev loj hlob?
Puas yog xav tau kev kho mob nrog G-CSF yog nyob ntawm:
- Hom thiab theem ntawm lymphoma
- Cov kws khomob
- Seb neutropenic sepsis tau tshwm sim yav dhau los
- Kev kho mob yav dhau los
- Muaj hnub nyoog
- Kev noj qab haus huv
Indications rau G-CSF
Muaj ntau qhov laj thawj vim li cas cov neeg mob qog ntshav qog ntshav yuav tsum tau txais G-CSF. Cov laj thawj tuaj yeem suav nrog:
- Tiv thaiv neutropenic sepsis. Kev kho mob rau lymphoma lub hom phiaj tua cov qog ntshav qog ntshav tab sis qee lub hlwb noj qab haus huv kuj tseem yuav cuam tshuam. Qhov no suav nrog cov qe ntshav dawb hu ua neutrophils. Kev kho mob nrog G-CSF pab kev suav neutrophil kom rov zoo sai dua. Nws tuaj yeem siv los txo qhov kev pheej hmoo ntawm neutropenic sepsis. Lawv kuj tuaj yeem tiv thaiv kev ncua lossis txo koob tshuaj hauv cov tshuaj khomob.
- Kho neutropenic sepsis. Neutropenic sepsis yog thaum tus neeg mob uas tsis tshua muaj neutrophils tau kis tus kab mob uas lawv tsis tuaj yeem tawm tsam thiab ua septic. Yog tias lawv tsis tau txais kev kho mob sai, nws tuaj yeem ua rau muaj kev hem thawj rau lub neej.
- Txhawm rau boost qia cell ntau lawm thiab mobilization ua ntej hloov pob txha pob txha. Kev loj hlob yam txhawb nqa cov pob txha pob txha los ua cov qia hlwb loj. Lawv kuj txhawb kom lawv txav tawm ntawm cov pob txha pob txha thiab mus rau hauv cov hlab ntsha, uas lawv tuaj yeem khaws tau yooj yim dua.
Nws muab li cas?
- G-CSF feem ntau yog txhaj rau hauv qab ntawm daim tawv nqaij (subcutaneously)
- Thawj txhaj tshuaj yog muab nyob rau hauv tsev kho mob saib xyuas rau tej yam tshwm sim
- Tus kws saib xyuas neeg mob tuaj yeem qhia tus neeg mob lossis tus neeg txhawb nqa yuav txhaj G-CSF hauv tsev li cas.
- Tus kws saib xyuas neeg mob hauv zej zog tuaj yeem tuaj xyuas txhua hnub kom txhaj tshuaj, lossis tuaj yeem muab rau ntawm GP phais.
- Lawv feem ntau tuaj nyob rau hauv ib leeg-siv, pre-filled syringes
- G-CSF txhaj tshuaj yuav tsum muab cia rau hauv lub tub yees.
- Nqa cov tshuaj tawm ntawm lub tub yees 30 feeb ua ntej nws xav tau. Nws yooj yim dua yog tias nws yog chav tsev kub.
- Cov neeg mob yuav tsum ntsuas lawv qhov kub thiab txias txhua hnub thiab ceeb toom rau lwm cov tsos mob ntawm tus kab mob.
Kev mob tshwm sim ntawm G-CSF txhaj tshuaj
Cov qib ntshav dawb hauv lub cev yuav raug kuaj tsis tu ncua nrog kev kuaj ntshav thaum cov neeg mob tau txhaj G-CSF.
Cov kev mob tshwm sim ntau dua
- xeev siab
- Ntuav
- Mob pob txha
- npaws
- nkees nkees
- Cov plaub hau tsis
- Mob plab los yog cem quav
- Kauj taub hau
- Qhib
- mob taub hau
Nco ntsoov: Qee tus neeg mob tuaj yeem raug mob ntawm pob txha hnyav, tshwj xeeb tshaj yog nyob rau sab nraub qaum. Qhov no tshwm sim raws li kev txhaj tshuaj G-CSF ua rau muaj kev nce ntxiv hauv cov neutrophils thiab cov lus teb rau hauv cov pob txha. Cov pob txha pob txha feem ntau yog nyob hauv pelvic (hip / sab nraub qaum). Qhov no tshwm sim thaum cov qe ntshav dawb rov qab los. Tus neeg mob yau dua qhov mob ntau dua, vim cov pob txha pob txha tseem hnyav heev thaum hluas. Tus neeg mob laus muaj cov pob txha pob txha tsawg thiab feem ntau mob tsawg tab sis tsis tas li. Tej yam uas tuaj yeem pab daws qhov tsis xis nyob:
- Paracetamol
- Kub pob
- Loratadine: ib qho ntawm cov tshuaj tiv thaiv antihistamine, uas txo cov inflammatory teb
- Hu rau pab neeg kho mob kom tau txais kev ua kom muaj zog ntxiv yog tias qhov saum toj no tsis pab
Tshaj tawm cov kev mob tshwm sim hnyav rau koj pab neeg kho mob.
Tsis tshua muaj tshwm sim
Qee tus neeg mob tuaj yeem tau txais tus po loj. Qhia rau tus kws kho mob yog tias koj muaj:
- Ib qho kev xav puv lossis tsis xis nyob ntawm sab laug ntawm lub plab, nyob hauv qab tav
- Mob ntawm sab laug ntawm lub plab
- Mob ntawm qhov kawg ntawm lub xub pwg sab laug
